drugset / Trial / NCT00534677
The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed
RandomizedParallel-groupTriple-blindTreatment
Summary
Terlipressin and Octreotide are two common agents used as adjuvants in the management of variceal bleeding. Both agents have been claimed equivalent to endoscopic therapy in randomized studies. There are no head to head clinical trials of these two agents available in the literature. We aimed to compare the efficacy and safety of Terlipressin and Octreotide in combination with Endoscopic Variceal band Ligation (EVL)in patients presenting with Esophageal Variceal Bleed (EVB).
Timeline
- Start
- 2004-05
- Primary completion
- —
- Completion
- 2005-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Octreotide | Peptide | 50 ug | — |
| Comparator | Terlipressin | Peptide | 1 mg | Intravenous |