drugset / Trial / NCT00534677

The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed

NCT00534677

Phase 4 Completed 320 enrolled Aga Khan University
RandomizedParallel-groupTriple-blindTreatment

Summary

Terlipressin and Octreotide are two common agents used as adjuvants in the management of variceal bleeding. Both agents have been claimed equivalent to endoscopic therapy in randomized studies. There are no head to head clinical trials of these two agents available in the literature. We aimed to compare the efficacy and safety of Terlipressin and Octreotide in combination with Endoscopic Variceal band Ligation (EVL)in patients presenting with Esophageal Variceal Bleed (EVB).

Timeline

Start
2004-05
Primary completion
Completion
2005-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Octreotide Peptide 50 ug
Comparator Terlipressin Peptide 1 mg Intravenous