drugset / Trial / NCT00534833

Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB-PRP~T Combined Vaccine or Tritanrix-HepB/Hib™

NCT00534833

Phase 3 Completed 362 enrolled Sanofi Pasteur, a Sanofi Company
Non-randomizedParallel-groupOpen-labelPrevention

Summary

The present trial is a follow-up of AL203 study (NCT00343889). Primary Objectives: To describe the antibody persistence at 15 to 18 months of age and the booster effect of a dose of DTaP-HB-PRP\~T or Tritanrix-HepB/Hib™ (given concomitantly with Oral Polio Vaccine \[OPV\]). Secondary Objective: To describe the safety profile of a booster dose of DTaP-HB-PRP\~T or Tritanrix-HepB/Hib™ when administered concomitantly with OPV in each vaccine group.

Timeline

Start
2007-09
Primary completion
2008-09
Completion
2009-03

Drugs

EvaluationDrugModalityDoseRoute
Subject DTaP-HB-PRP~T vaccine Vaccine 0.5 ml Intramuscular
Comparator Tritanrix-HepB/Hib™ Vaccine 0.5 ml Intramuscular
Background Oral Polio Vaccine Vaccine 0.5 ml Oral