drugset
drugset / Trial / NCT00535002

The Effect of Yohimbine on Cocaine Cue Reactivity

NCT00535002 ↗

Phase 2 Completed 112 enrolled Medical University of South Carolina National Institute on Drug Abuse (NIDA) · collabOffice of Research on Women's Health (ORWH) · collab
RandomizedCrossoverDouble-blindTreatment

Summary

Stress and cues reminiscent of cocaine use promote craving and relapse in cocaine dependent individuals. In addition, there appears to be gender differences in determinants of relapse to drug use following abstinence in cocaine-dependent individuals. Therefore the purpose of the present study is to study the role of hormonal status on the response to cocaine-related cues with or without stress in cocaine-dependent women and men.

Timeline

Start
2007-09
Primary completion
2012-08
Completion
2012-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Yohimbine Small molecule — —

Indications

cocaine dependence