drugset / Trial / NCT00535366
Efficacy and Safety Comparison of Steroid or Placebo in Combination With Salmeterol and Tiotropium in COPD
RandomizedCrossoverDouble-blindTreatment
Summary
This efficacy and safety study compares four different combinations of blinded inhaled steroid treatments on top of open-label tiotropium and salmeterol in patients with chronic obstructive pulmonary disease (COPD). The primary objective is the effect on lung function parameters.
Timeline
- Start
- 2007-10
- Primary completion
- 2008-09
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ciclesonide | Other / unclassified | 400 ug | Inhaled |
| Subject | Ciclesonide | Other / unclassified | 800 ug | Inhaled |
| Subject | Fluticasone | Other / unclassified | 500 ug | Inhaled |
| Background | Salmeterol | Other / unclassified | 50 ug | Inhaled |
| Background | Tiotropium | Other / unclassified | 18 ug | Inhaled |