drugset / Trial / NCT00536640
Inoperable Non-Squamous NSCLC Stage III/IV: A Randomised Phase II Study With Bevacizumab Plus Erlotinib Or Gemcitabine/Cisplatin Plus Bevacizumab
RandomizedParallel-groupOpen-labelTreatment
Summary
This study wants to determine the activity of a non chemotherapy first line biological treatment with Erlotinib/Bevacizumab or Gemcitabine-Cisplatin/Bevacizumab in patients with the diagnosis of non-squamous advanced Non Small Lung Cancer.
Timeline
- Start
- 2007-11
- Primary completion
- 2011-08
- Completion
- 2012-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 15 mg/kg | Intravenous |
| Comparator | Cisplatin | Other / unclassified | 80 mg/m2 | Intravenous |
| Subject | Erlotinib | Small molecule | 150 mg | Oral |
| Comparator | Gemcitabine | Small molecule | 1250 mg/m2 | Intravenous |