The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients

Phase 2/3 Unknown 65 enrolled National Institute for Medical Research, Tanzania Danone Institute International · collab Erasmus Medical Center · collab London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · collab Sekou-Toure Regional Hosipital, Mwanza, Tanzania · collab University of Western Ontario, Canada · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to asses whether probiotics Lactobacillus rhamnosus (GR-1) and reuteri (RC-14) are able to prevent diarrhea, delay the decline of the immune system and prevent and/or cure bacterial vaginosis among HIV patients.

Timeline

Start: 2007-10
Primary completion: 2008-08
Completion: 2008-08

Publications

Hummelen R, Changalucha J, Butamanya NL, Cook A, Habbema JD, Reid G. Lactobacillus rhamnosus GR-1 and L. reuteri RC-14 to prevent or cure bacterial vaginosis among women with HIV. Int J Gynaecol Obstet. 2010 Dec;111(3):245-8. doi: 10.1016/j.ijgo.2010.07.008.

Drugs

Evaluation	Drug	Modality	Dose	Route
Background	Metronidazole	Small molecule	400 mg	—

The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients

Summary

Timeline

Publications

Drugs

Indications