drugset / Trial / NCT00542529

Phase I/II, Randomized, Double-Blind, Study of the Progenitor Cell Mobilizing Effects of Imprime PGG™ Injection Administered at Varied Dosing Regimens With G-CSF Versus G-CSF Alone

NCT00542529

Phase 1/2 Completed 66 enrolled HiberCell, Inc.
RandomizedParallel-groupTriple-blind

Summary

This study is a randomized, placebo-controlled, dose-escalation, single-center study evaluating two different doses of Imprime PGG, each in 7 different dosing regimes. A total of 66 subjects will be enrolled into 2 cohorts and, within each cohort, randomized to 1 of 7 treatment groups receiving Imprime PGG or placebo in varied dosing regimens with granulocyte-colony stimulating factor (G-CSF).

Timeline

Start
2006-11
Primary completion
Completion
2006-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Imprime PGG Other / unclassified 2 mg/kg Intravenous
Comparator Imprime PGG Other / unclassified 4 mg/kg Intravenous

Indications

No indication recorded.