drugset / Trial / NCT00542893
A Phase I, Randomized, Open-label, Cross-over, Pharmacokinetic Study of Genasense With and Without Dacarbazine
RandomizedCrossoverOpen-labelTreatment
Summary
This clinical drug-drug interaction study is being conducted to evaluate the pharmacokinetics of dacarbazine(DTIC) when administered in combination with Genasense
Timeline
- Start
- 2006-04
- Primary completion
- —
- Completion
- 2007-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dacarbazine | Small molecule | 1000 mg/m2 | — |
| Subject | oblimersen sodium | Antisense oligonucleotide | 7 mg/kg | — |