A Phase IIa Study Of Men And Post-Menopausal Women With A Fractured Distal Radius

Phase 2 Terminated 86 enrolled GlaxoSmithKline

RandomizedParallel-groupDouble-blindTreatment

Summary

This is a study designed to test the safety and effectiveness of SB-751689 in the treatment of a distal radius fracture in post-menopausal women and men in comparison to placebo to determine if healing time of the fracture can be decreased.

Timeline

Start: 2007-09-20
Primary completion: 2008-11-26
Completion: 2008-11-26

Publications

Fitzpatrick LA, Smith PL, McBride TA, Fries MA, Hossain M, Dabrowski CE, Gordon DN. Ronacaleret, a calcium-sensing receptor antagonist, has no significant effect on radial fracture healing time: results of a randomized, double-blinded, placebo-controlled Phase II clinical trial. Bone. 2011 Oct;49(4):845-52. doi: 10.1016/j.bone.2011.06.017. Epub 2011 Jun 30.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	SB-751689	Unknown	200 mg	Oral
Subject	SB-751689	Unknown	400 mg	Oral

Indications

No indication recorded.