Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM

Summary

The purpose of this study is to determine the safety and efficacy of the combination of Gliadel wafers plus surgery and limited field radiation therapy with concomitant temozolomide followed by temozolomide given at an extended dose schedule (metronomic schedule) in patients undergoing initial surgery for newly-diagnosed high grade glioma.

Timeline

Start

2007-10

Primary completion

2009-10

Completion

2010-10

Drugs

Indications