drugset / Trial / NCT00549601

Convenience, Tolerability, and Safety of Change in the Administration of Rivastigmine From Capsules to a Transdermal Patch in Patients With Mild to Moderate Alzheimer's Disease

NCT00549601

Phase 4 Completed 142 enrolled Novartis
RandomizedParallel-groupOpen-labelTreatment

Summary

This study used two doses of rivastigmine transdermal patch (5 cm\^2, 10 cm\^2) to establish the feasibility of 2 switch schedules (with transdermal patch one-step dose titration or without dose titration) from rivastigmine capsules (3 mg bid (bis in die, twice a day), 4,5 mg bid, 6 mg bid) to rivastigmine transdermal patch and to assess safety, tolerability, convenience, and caregivers preferences of rivastigmine transdermal patch versus capsules.

Timeline

Start
2007-09
Primary completion
2009-04
Completion
2009-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Rivastigmine Small molecule 6 mg Other
Subject Rivastigmine Small molecule 9 mg Other
Subject Rivastigmine Small molecule 9.5 mg Other
Subject Rivastigmine Small molecule 12 mg Other

Indications