drugset / Trial / NCT00549601
Convenience, Tolerability, and Safety of Change in the Administration of Rivastigmine From Capsules to a Transdermal Patch in Patients With Mild to Moderate Alzheimer's Disease
RandomizedParallel-groupOpen-labelTreatment
Summary
This study used two doses of rivastigmine transdermal patch (5 cm\^2, 10 cm\^2) to establish the feasibility of 2 switch schedules (with transdermal patch one-step dose titration or without dose titration) from rivastigmine capsules (3 mg bid (bis in die, twice a day), 4,5 mg bid, 6 mg bid) to rivastigmine transdermal patch and to assess safety, tolerability, convenience, and caregivers preferences of rivastigmine transdermal patch versus capsules.
Timeline
- Start
- 2007-09
- Primary completion
- 2009-04
- Completion
- 2009-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rivastigmine | Small molecule | 6 mg | Other |
| Subject | Rivastigmine | Small molecule | 9 mg | Other |
| Subject | Rivastigmine | Small molecule | 9.5 mg | Other |
| Subject | Rivastigmine | Small molecule | 12 mg | Other |