drugset / Trial / NCT00550147
Quetiapine and Concerta in the Treatment for ADHD and Aggressive Behavior.
NaSingle-groupOpen-labelTreatment
Summary
The primary purpose of this thirteen-week, open-label study is to test the hypothesis that quetiapine in combination with Oros methylphenidate will reduce aggressive symptoms in children and adolescents who have shown inadequate response to OROS methylphenidate alone.
Timeline
- Start
- 2004-02
- Primary completion
- 2005-11
- Completion
- 2005-11
Outcome
Met primary endpoint
registry p <0.05; Mean Difference (Final Values) -1.125 (95% CI -1.52 to -0.72); t-test, 2 sided NCT00550147 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylphenidate | Small molecule | 54 mg | — |
| Subject | Quetiapine | Small molecule | 25 mg | — |
| Subject | Quetiapine | Small molecule | 50 mg | — |
| Subject | Quetiapine | Small molecule | 100 mg | — |
| Subject | Quetiapine | Small molecule | 200 mg | — |
| Subject | Quetiapine | Small molecule | 300 mg | — |