drugset / Trial / NCT00550381
Study Evaluating the Safety, Tolerability, and Pharmacokinetics (PK) of HKI-357 Administered Orally to Healthy Subjects
RandomizedSingle-groupDouble-blindTreatment
Summary
The purpose of this study is to assess the safety, tolerability, and pharmacokinetics of single doses of HKI-357 administered to healthy subjects.
Timeline
- Start
- 2008-01
- Primary completion
- 2008-03
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | HKI-357 | Small molecule | 10 mg | Oral |
| Comparator | HKI-357 | Small molecule | 20 mg | Oral |
| Comparator | HKI-357 | Small molecule | 40 mg | Oral |
| Comparator | HKI-357 | Small molecule | 80 mg | Oral |
| Comparator | HKI-357 | Small molecule | 160 mg | Oral |
| Comparator | HKI-357 | Small molecule | 240 mg | Oral |
| Comparator | HKI-357 | Small molecule | 400 mg | Oral |
| Comparator | HKI-357 | Small molecule | 640 mg | Oral |
| Comparator | HKI-357 | Small molecule | 960 mg | Oral |
Indications
No indication recorded.