drugset / Trial / NCT00551772

A Study To Assess The Pharmacokinetics Of SB-742457 Formulated As A Capsule And A Tablet In Healthy Elderly Volunteers.

NCT00551772

Phase 1 Completed 12 enrolled GlaxoSmithKline
RandomizedCrossoverOpen-labelTreatment

Summary

SB-742457 is a 5HT6 receptor antagonist that is in development for the symptomatic treatment of mild to moderate Alzheimer's disease . To date, all clinical trials have been conducted using a capsule formulation of SB-742457. However, it is intended to conduct all futures studies with a tablet formulation. The aim of this study is to assess the pharmacokinetic profile of SB-742457 and its major metabolites following single doses of both the capsule and tablet formulations.

Timeline

Start
2007-08
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject intepirdine Small molecule

Indications