Quetiapine Induced Neuroplasticity in First-episode Schizophrenic Patients

Summary

Aim of the study is to assess the effect of quetiapine treatment in neuroleptic naive, first-episode schizophrenic patients on aspects of functional and structural neuroplasticity assessed by means of transcranial magnetic stimulation and voxel-based morphometry. Main outcome measure is a change in gray matter density under quetiapine treatment from baseline to steady-state-treatment after 3 weeks.

Timeline

Start

2008-03

Primary completion

2010-12

Completion

2011-03

Drugs

Indications