Effects of HMG-coA Reductase Inhibitor on Rheumatoid Arthritis

Summary

The purpose of this study is: 1. To evaluate the prevalence of preclinical atherosclerosis in Chinese patients with RA compared to healthy controls. 2. To determine those clinical and biological measures that best predict the presence of plaque and increased arterial stiffness. 3. To ascertain the efficacy and safety of rosuvastatin in the prevention of atherosclerosis in patients with RA measured by carotid intima-media thickness (IMT) and pulse wave velocity (PWV).

Timeline

Start

2007-07

Primary completion

2009-12

Completion

2009-12

Drugs

Indications