drugset

drugset / Trial / NCT00556361

Use of Ketamine Prior to Cardiopulmonary Bypass in Children

NCT00556361 ↗

Phase 2 Completed 24 enrolled Arkansas Children's Hospital Research Institute

Non-randomizedParallel-groupTriple-blindPrevention

Summary

To assess whether the drug ketamine given prior to cardiopulmonary bypass can decrease injury to the cells in the brain.

Timeline

Start: 2004-07
Primary completion: —
Completion: 2007-11

Publications

Bhutta AT, Schmitz ML, Swearingen C, James LP, Wardbegnoche WL, Lindquist DM, Glasier CM, Tuzcu V, Prodhan P, Dyamenahalli U, Imamura M, Jaquiss RD, Anand KJ. Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial. Pediatr Crit Care Med. 2012 May;13(3):328-37. doi: 10.1097/PCC.0b013e31822f18f9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ketamine	Small molecule	2 mg/kg	Intravenous

Indications