drugset / Trial / NCT00557791
Safety & Efficacy Study Evaluating the Combination of Bevasiranib & Lucentis Therapy in Wet AMD (CARBON)
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to compare the safety and effectiveness of three doses of intravitreal bevasiranib sodium as maintenance therapy for Age-Related Macular Degeneration following initiation of anti-VEGF therapy with three doses of Lucentis®.
Timeline
- Start
- 2009-11
- Primary completion
- 2011-07
- Completion
- 2012-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ranibizumab | Monoclonal antibody | 0.5 mg | Intravitreal |
| Subject | bevasiranib | Unknown | 1 mg | Intravitreal |
| Subject | bevasiranib | Unknown | 2 mg | Intravitreal |
| Subject | bevasiranib | Unknown | 2.5 mg | Intravitreal |