drugset / Trial / NCT00557791

Safety & Efficacy Study Evaluating the Combination of Bevasiranib & Lucentis Therapy in Wet AMD (CARBON)

NCT00557791

Phase 3 Withdrawn OPKO Health, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to compare the safety and effectiveness of three doses of intravitreal bevasiranib sodium as maintenance therapy for Age-Related Macular Degeneration following initiation of anti-VEGF therapy with three doses of Lucentis®.

Timeline

Start
2009-11
Primary completion
2011-07
Completion
2012-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ranibizumab Monoclonal antibody 0.5 mg Intravitreal
Subject bevasiranib Unknown 1 mg Intravitreal
Subject bevasiranib Unknown 2 mg Intravitreal
Subject bevasiranib Unknown 2.5 mg Intravitreal