Coronary MDCTA With Iopamidol Injection 370

Summary

Determine the validity and compare the visualization of arterial segments obtained with 3 doses of iopamidol to determine dose for further investigation in future trials.

Timeline

Start

2007-11

Primary completion

2010-05

Completion

2010-05

Outcome

Mixed primary results

registry NUMBER Isovue 370, 70 mL: 949 Segments Visualized Accurately NCT00558792 ↗

registry analysis (superiority or other test); Isovue 370, 70 mL vs Isovue 370, 80 mL vs Isovue 370, 90 mL; p = 0.0099; Chi-squared NCT00558792 ↗

registry NUMBER Isovue 370, 70 mL: 925 Segments Visualized Accurately NCT00558792 ↗

registry analysis (superiority or other test); Isovue 370, 70 mL vs Isovue 370, 80 mL vs Isovue 370, 90 mL; p = 0.1212; Chi-squared NCT00558792 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Iopamidol	Diagnostic / imaging agent	70 ml	—
Subject	Iopamidol	Diagnostic / imaging agent	80 ml	—
Subject	Iopamidol	Diagnostic / imaging agent	90 ml	—

Indications