drugset / Trial / NCT00560937

Pilot Study of Pregnenolone Augmentation Targeting Cognitive Symptoms in Persistently Symptomatic Patients With Schizophrenia

NCT00560937

Completed 28 enrolled Durham VA Medical Center
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a pilot study of pregnenolone as an augmentation treatment for schizophrenia. The goal of this placebo-controlled study is to provide preliminary efficacy data for potential pregnenolone effects on cognitive symptoms and negative symptoms in patients with schizophrenia. Depressive symptoms and positive symptoms will also be assessed.

Timeline

Start
2005-06
Primary completion
2006-04
Completion
2008-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pregnenolone Other / unclassified 250 mg

Indications