Comparison of the Efficacy of Topical Ibuprofen to Oral Ibuprofen in Adolescent Athletes

Terminated 60 enrolled Akron Children's Hospital

RandomizedParallel-groupTriple-blindTreatment

Summary

This study was made to compare the efficacy of topical ibuprofen in gel form with oral ibuprofen in the treatment of sub-acute soft tissue injuries while comparing the tolerability of the delivery methods

Timeline

Start: 2006-05
Primary completion: 2009-04
Completion: 2009-04

Publications

Background Whitefield M, O'Kane CJ, Anderson S. Comparative efficacy of a proprietary topical ibuprofen gel and oral ibuprofen in acute soft tissue injuries: a randomized, double-blind study. J Clin Pharm Ther. 2002 Dec;27(6):409-17. doi: 10.1046/j.1365-2710.2002.00439.x.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ibuprofen	Small molecule	0.5 ml	Topical
Subject	Ibuprofen	Small molecule	10 %	Topical
Subject	Ibuprofen	Small molecule	10 mg/kg	Topical
Subject	Ibuprofen	Small molecule	40 mg/kg	Topical

Indications

No indication recorded.