Study of Maca Root for the Treatment of Antidepressant-Induced Sexual Dysfunction in Females

Phase 3 Completed 45 enrolled Massachusetts General Hospital A Healthy Alternative, LLC · collab National Center for Complementary and Integrative Health (NCCIH) · collab National Institutes of Health (NIH) · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to find out whether Maca Root is effective for treating sexual dysfunction in females that is caused by antidepressant drugs. An additional aim of the study is to document the safety and tolerability of maca root, as well as any potential side effects that it causes.

Timeline

Start: 2007-12-27
Primary completion: 2010-10-05
Completion: 2010-10-05

Outcome

Missed primary endpoint

registry Maca Root vs Placebo; p = 0.55; Odds Ratio (OR) 2.1 (95% CI 0.18 to 25.2); NCT00568126 ↗

registry Maca Root vs Placebo; p = 0.47; Odds Ratio (OR) 1.71 (95% CI 0.40 to 7.34); NCT00568126 ↗

Publications

Results Dording CM, Schettler PJ, Dalton ED, Parkin SR, Walker RS, Fehling KB, Fava M, Mischoulon D. A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evid Based Complement Alternat Med. 2015;2015:949036. doi: 10.1155/2015/949036. Epub 2015 Apr 14.

Drugs