drugset / Trial / NCT00569569

Retaane® in Age-Related Macular Degeneration

NCT00569569

Phase 2/3 Completed 20 enrolled Rudolf Foundation Clinic
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The treatment of fibrotic choroidal neovascular lesions with presence of residual peripheral activity in age related macular degeneration currently presents a great challenge. With visual loss threatening, there are only very few therapeutic options. While these patients are neither suitable for laser therapy nor for photodynamic therapy with Verteporfin, antiangiogenic drugs applied intravitreally are now available. Some patients however reject this therapeutic option because of potential complications such as endophthalmitis and the frequency of necessary injections. 20 patients who rejected intravitreal therapy were treated with Anecortave acetate (Retaane®) which was applied as a juxtascleral depot injection.

Timeline

Start
2006-02
Primary completion
Completion
2007-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Anecortave Acetate Small molecule Other