Safety and Tolerability of Inhaled Nitric Oxide in Patients With Cystic Fibrosis

Summary

The primary objective of the trial is to assess the safety and tolerability of inhaled nitric oxide (NO) when administered by nasal cannula over a 44 hour period to clinically stable Cystic Fibrosis (CF) subjects. Toxicity is to be defined as a drop in oxygen saturations, a decline in forced expiratory volume in one second (FEV1), or an increase in methemoglobin.

Timeline

Start

2004-07

Primary completion

2008-12

Completion

2008-12

Drugs

Indications