Prucalopride in Patients With Chronic Idiopathic Constipation

Summary

The purpose of this study is to determine whether prucalopride is safe and effective in the treatment of chronic idiopathic constipation. Hypothesis: Prucalopride given at a dose of 1 mg o.d. for 4 weeks to female patients with chronic constipation shows a favourable effect on most of the efficacy parameters assessed in this trial. This dosage can be considered safe and generally well-tolerated.

Timeline

Start

1997-04

Primary completion

1999-03

Completion

1999-03

Publications

• Results Emmanuel AV, Roy AJ, Nicholls TJ, Kamm MA. Prucalopride, a systemic enterokinetic, for the treatment of constipation. Aliment Pharmacol Ther. 2002 Jul;16(7):1347-56. doi: 10.1046/j.1365-2036.2002.01272.x.

Drugs

Indications