Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma

Phase 2 Completed 25 enrolled Marmara University Schering-Plough · collab

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy of temozolomide on a protracted schedule, after standard 5-day temozolomide regimen in patients with recurrent or progressive high grade glioma.

Timeline

Start: 2006-08
Primary completion: 2009-03
Completion: 2009-03

Publications

Results Abacioglu U, Caglar HB, Yumuk PF, Akgun Z, Atasoy BM, Sengoz M. Efficacy of protracted dose-dense temozolomide in patients with recurrent high-grade glioma. J Neurooncol. 2011 Jul;103(3):585-93. doi: 10.1007/s11060-010-0423-2. Epub 2010 Sep 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Temozolomide	Small molecule	100 mg/m2	Oral

Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma

Summary

Timeline

Publications

Drugs

Indications