drugset / Trial / NCT00586521
BAY14-2222 Prophylaxis and Joint Function Improvement (Adults)
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of the study is to evaluate the effect of prophylactic treatment on the number of joint bleeds and quality of life in severe hemophilia A subjects compared to on-demand treatment in a one-group two-treatment schedule design. In addition, the effect of prophylactic treatment on the joint function, the number of all bleeds, and on the quality of life compared to on-demand treatment and health-economic data will be assessed.
Timeline
- Start
- 2006-02
- Primary completion
- 2008-03
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ADVATE | Protein / enzyme biologic | 20 iu/kg | — |
| Subject | ADVATE | Protein / enzyme biologic | 40 iu/kg | — |