drugset / Trial / NCT00589186

Vaccine Therapy and Celecoxib in Treating Patients With Metastatic Nasopharyngeal Cancer

NCT00589186 ↗

Phase 2 Unknown 35 enrolled National Cancer Centre, Singapore
Non-randomizedOpen-labelTreatment

Summary

RATIONALE: Vaccines made from a gene-modified virus and a person's dendritic cells may help the body build an effective immune response to kill tumor cells. Celecoxib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving vaccine therapy together with celecoxib may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving vaccine therapy together with celecoxib works in treating patients with metastatic nasopharyngeal cancer.

Timeline

Start
2007-11
Primary completion
2009-12
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject AD5F35-LMP-1/LMP-2 Cell therapy — Intramuscular
Subject Celecoxib Other / unclassified — —

Indications