drugset / Trial / NCT00593879
Flexible Dose Titration Add-on Study to Treat Major Depressive Disorder
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Depressed patients will receive 6 weeks of citaloprma (20-40mg) therapy. Subjects who have an inadequate response (partial or non-responder) will be randomized to receive either mecamylamine (5-10mg) or placebo added to their citalopram for a further 8 weeks.
Timeline
- Start
- 2005-02
- Primary completion
- —
- Completion
- 2006-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mecamylamine | Small molecule | 5 mg | — |
| Subject | Mecamylamine | Small molecule | 7.5 mg | — |
| Subject | Mecamylamine | Small molecule | 10 mg | — |