drugset / Trial / NCT00597480

Study of Growth-promoting and Metabolic Effects of Growth Hormone (rhGH)

NCT00597480 ↗

RandomizedParallel-groupOpen-labelTreatment

Summary

Recombinant growth hormone (rhGH) treatment is widely used in France to normalize height during childhood and final height in children born small for gestational age (SGA). Because rhGH has been associated with increased insulin levels and insulin resistance, concern has been expressed regarding the late consequences of rhGH treatment on risk factors for diabetes mellitus type II and metabolic syndrome, especially in possibly predisposed subjects as SGA children.

Timeline

Start
2008-01
Primary completion
2012-01
Completion
2012-01

Outcome

Outcome not reported

Stopped: “no more inclusions”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Norditropine SimpleXx® Protein / enzyme biologic 0.067 mg/kg —