Effect of Omacor on Triglycerides in HIV Infected Subjects

Phase 4 Terminated 51 enrolled Solvay Pharmaceuticals

RandomizedParallel-groupDouble-blindTreatment

Summary

Omacor is likely to decrease lipid parameters in HIV infected subjects. In these subjects the lipid are decrease due to HAART treatment

Timeline

Start: 2007-08
Primary completion: 2008-09
Completion: 2009-03

Outcome

Met primary endpoint

Stopped (Enrollment): “The study was discontinued prematurely on December 18 2008 due to slow recruitment”

paper PUFA therapy with DHA/EPA reduced triglyceride levels significantly compared with placebo in HIV-infected patients with HAART-associated hypertriglyceridemia. PMID 22212377 ↗

Publications

Peters BS, Wierzbicki AS, Moyle G, Nair D, Brockmeyer N. The effect of a 12-week course of omega-3 polyunsaturated fatty acids on lipid parameters in hypertriglyceridemic adult HIV-infected patients undergoing HAART: a randomized, placebo-controlled pilot trial. Clin Ther. 2012 Jan;34(1):67-76. doi: 10.1016/j.clinthera.2011.12.001. Epub 2011 Dec 31.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lovaza	Other / unclassified	4 g	—