drugset / Trial / NCT00603616
Induction of Clinical Response Using Rifaximin in Crohn's Disease
RandomizedCrossoverTriple-blindTreatment
Summary
Antibiotics have been used to treat Crohn's disease symptoms with the best studied antibiotics being Cipro and Flagyl. Rifaximin is a poorly absorbed oral antibiotic that is FDA approved for travelers' diarrhea. It works by inhibiting bacterial reproduction. It is very poorly absorbed and over 97% of the drug taken orally is excreted in the feces. The purpose of this study is to evaluate the potential benefits and safety of Rifaximin for the treatment of moderate to severe symptoms of Crohn's Disease.
Timeline
- Start
- 2008-11
- Primary completion
- 2020-11-03
- Completion
- 2020-11-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Rifaximin | Other / unclassified | 550 mg | Oral |