drugset / Trial / NCT00603616

Induction of Clinical Response Using Rifaximin in Crohn's Disease

NCT00603616

Phase 2 Completed 36 enrolled Scott Lee Bausch Health Americas, Inc. · collab
RandomizedCrossoverTriple-blindTreatment

Summary

Antibiotics have been used to treat Crohn's disease symptoms with the best studied antibiotics being Cipro and Flagyl. Rifaximin is a poorly absorbed oral antibiotic that is FDA approved for travelers' diarrhea. It works by inhibiting bacterial reproduction. It is very poorly absorbed and over 97% of the drug taken orally is excreted in the feces. The purpose of this study is to evaluate the potential benefits and safety of Rifaximin for the treatment of moderate to severe symptoms of Crohn's Disease.

Timeline

Start
2008-11
Primary completion
2020-11-03
Completion
2020-11-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Rifaximin Other / unclassified 550 mg Oral

Indications