Dose Milnacipran Prevent Depressive Symptoms in Patients With Acute Stroke?

Summary

Depression is one of the important psychiatric sequelae after stroke. The prevalence of post stroke depression (PSD) is approximately 20-40%. Depression comorbid with stroke has been found to be associated with increased disability, cognitive function decline, poorer rehabilitation outcome and higher mortality rate.We are going to conduct a trial of prevention of psot stroke depression by prescribing milnacipran in advance.

Timeline

Start

2007-09

Primary completion

2010-09

Completion

2011-09

Drugs

Indications