drugset / Trial / NCT00606242
Dose Response Effects of Inhaled Fluticasone on Airway Effects of Hypertonic-saline in Asthma
Phase 4
Completed
44 enrolled
University of California, San Francisco
GlaxoSmithKline · collabNational Heart, Lung, and Blood Institute (NHLBI) · collab
RandomizedParallel-groupDouble-blindBasic science
Summary
This study investigates the effect of a inhaled corticosteroid (fluticasone or "Flovent") on airway narrowing induced by hypertonic saline (salty water). The study hypothesis is that fluticasone will be more effective in preventing saline-induced airway narrowing than methacholine-induced narrowing.
Timeline
- Start
- 2000-01
- Primary completion
- 2002-12
- Completion
- 2007-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluticasone | Other / unclassified | 100 ug | Inhaled |
| Comparator | Fluticasone | Other / unclassified | 1000 ug | Inhaled |