Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus

Summary

Elevations of plasma cortisol, a stress hormone, during prior episodes of low blood sugar (hypoglycemia) appear to be responsible for the deficient responses during subsequent hypoglycemia. Our specific aim is to determine if dehydroepiandrosterone (DHEA), a hormone with anti-corticosteroid actions, can prevent hypoglycemia associated autonomic failure in type 1 diabetic volunteers.

Timeline

Start

2010-10

Primary completion

2018-10-09

Completion

2018-10-09

Drugs

Indications