Glimepiride Induced Insulin Secretion Will be Inhibited by Hypoglycemia

Summary

This study will look at two FDA approved medications that improve how the pancreas works in patients with Type 2 Diabetes. In order to understand how these medications work in patients with diabetes we must first measure the normal response in healthy volunteers without diabetes. We will be looking at the body's normal physiological response to low blood sugar and whether this will be modified by these medicationsThe hypothesis would be that glimepiride induced insulin secretion will be inhibited by hypoglycemia.

Timeline

Start

2002-08

Primary completion

2004-09

Completion

2010-12

Drugs

Indications