Pharmacokinetics of LCP-Tacro in Stable Liver Transplant Patients

Summary

A three sequence, open-label, multi-center, prospective, study in stable liver transplant patients to assess and compare the pharmacokinetics (Cmax, C24, and AUC), and safety of LCP-Tacro (tacrolimus) tablets versus Prograf (tacrolimus) capsules.

Timeline

Start

2007-11

Primary completion

2008-06

Completion

2008-06

Publications

• Alloway RR, Eckhoff DE, Washburn WK, Teperman LW. Conversion from twice daily tacrolimus capsules to once daily extended-release tacrolimus (LCP-Tacro): phase 2 trial of stable liver transplant recipients. Liver Transpl. 2014 May;20(5):564-75. doi: 10.1002/lt.23844. Epub 2014 Mar 26.

Drugs

Indications