drugset / Trial / NCT00608465

Defining Strategies for Improving Endothelial and Fibrinolytic Dysfunction in Obesity

NCT00608465

Phase 4 Terminated 4 enrolled Vanderbilt University
RandomizedParallel-groupDouble-blindPrevention

Summary

The combination of high blood pressure and having central obesity is an increasing important factor for heart disease in men and women. It can also lead to the early development of hardening of the arteries and increased risk of a stroke. This study will analyze patients' genetic make up to identify who may be at greater risk for heart disease and strokes in relationship to high blood pressure and central obesity.

Timeline

Start
2006-05
Primary completion
2009-05
Completion
2011-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Eplerenone Unknown 10 mg
Comparator Ramipril Small molecule 5 mg

Indications