drugset / Trial / NCT00610246

A Study of Radiation With Sorafenib in Advanced Cancer

NCT00610246 ↗

Phase 1 Completed 34 enrolled University Health Network, Toronto
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to test the combination of radiation treatment and an anti-angiogenic drug called sorafenib (or BAY 43-9006 or Nexavar) to determine the effects of this combination on cancers but also on side effects of radiation treatment. This study will also determine the highest safe dose of sorafenib that can be given with radiation treatment.

Timeline

Start
2007-05
Primary completion
2010-12
Completion
2011-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Sorafenib Small molecule 200 mg Oral
Subject Sorafenib Small molecule 400 mg Oral

Indications