drugset / Trial / NCT00611728

Ph I SU011248 + Irinotecan in Treatment of Pts w MG

NCT00611728

Phase 1 Completed 25 enrolled Duke University Pfizer · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Primary Objectives To determine maxi tolerated dose \& dose limiting toxicity of SU011248 + Irinotecan in recurrent MG pts not on EIAEDs To characterize safety \& tolerability of SU011248 + Irinotecan among pts w recurrent MG Secondary Objectives To evaluate pharmacokinetic profile of SU011248 \& Irinotecan when co-administered in pts w MG To evaluate anti-tumor activity of SU011248 + Irinotecan

Timeline

Start
2008-03
Primary completion
2010-06
Completion
2010-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule Intravenous
Subject Sunitinib Small molecule Oral

Indications