The Effect of Sertindole on Sensory Gating and Cognition in Healthy Volunteers

NCT00612079 ↗

Completed 30 enrolled University of Zurich H. Lundbeck A/S · collab Psychiatric University Hospital, Zurich · collab

RandomizedCrossoverDouble-blindBasic science

Summary

This study aims to further validate and extend our previous findings insofar that the effect of the atypical antipsychotic and mixed 5-HT2/D2 antagonist sertindole on sensorimotor gating processes and its relationship to cognitive performance shall be explored.

Timeline

Start: 2007-09
Primary completion: 2008-10
Completion: 2008-11

Publications

Results Holstein DH, Csomor PA, Geyer MA, Huber T, Brugger N, Studerus E, Vollenweider FX. The effects of sertindole on sensory gating, sensorimotor gating, and cognition in healthy volunteers. J Psychopharmacol. 2011 Dec;25(12):1600-13. doi: 10.1177/0269881111415734. Epub 2011 Sep 2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sertindole	Small molecule	4 mg	Oral

Indications

No indication recorded.