drugset / Trial / NCT00612339
Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomas
NaSingle-groupOpen-labelTreatment
Summary
Primary objective- To determine efficacy of Avastin, 10 mg/kg every other week, in combination with standard 5-day temozolomide in terms of response rate. Secondary objective- To determine safety of Avastin \& Temozolomide in unresectable glioblastoma patients
Timeline
- Start
- 2007-08
- Primary completion
- 2012-05
- Completion
- 2012-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 10 mg/kg | — |
| Subject | Temozolomide | Small molecule | 200 mg/m2 | — |