drugset / Trial / NCT00612573
Treatment of Moderate to Severe Facial Acne Vulgaris
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Randomized, multi-center, double-blind, placebo-controlled 12-week study to assess the safety and efficacy of 3 doses of an oral formulation of Doxycycline oral tablets using the Investigator's Global Assessment (IGA) score and the absolute change from baseline in inflammatory lesion count in patients with moderate to severe facial acne vulgaris. Additionally, the absolute change from baseline in non-inflammatory and total lesions of the active study medication to placebo will be evaluated.
Timeline
- Start
- 2008-02
- Primary completion
- 2008-11
- Completion
- 2008-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxycycline | Small molecule | 0.6 mg/kg | Oral |
| Subject | Doxycycline | Small molecule | 1.2 mg/kg | Oral |
| Subject | Doxycycline | Small molecule | 2.4 mg/kg | Oral |