drugset / Trial / NCT00612664

Phase II, 2nd Line Melanoma - RAND Monotherapy

NCT00612664

Phase 2 Completed 158 enrolled Bristol-Myers Squibb
RandomizedParallel-groupOpen-labelTreatment

Summary

The main purpose of this study is to estimate the proportion of patients with a type of skin cancer called melanoma who are progression free, (that is, the cancer has not gotten substantially worse), when treated with Anti-CD137 (4-1BB) (BMS-663513) at 0.1 mg/kg, 1 mg/kg or 5 mg/kg every 3 weeks or 1 mg/kg every 6 weeks

Timeline

Start
2008-03
Primary completion
2009-10
Completion
2009-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Urelumab Monoclonal antibody 0.1 mg/kg Intravenous
Comparator Urelumab Monoclonal antibody 1 mg/kg Intravenous
Comparator Urelumab Monoclonal antibody 5 mg/kg Intravenous

Indications