drugset / Trial / NCT00612898

Study of the Efficacy and Safety of Apricitabine, a New NRTI, to Treat Drug-resistant HIV Infection

NCT00612898

Phase 2/3 Terminated 239 enrolled Avexa
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Apricitabine is a new NRTI which is active against drug-resistant HIV. NRTIs are often included as part of patients' treatment, but many HIV-infected patients develop resistance to commonly used NRTIs such as lamivudine (3TC) and emtricitabine (FTC). This study will examine whether including apricitabine as part of patients' treatment is more effective than including lamivudine,when patients change treatment because of drug resistance.

Timeline

Start
2008-02
Primary completion
2010-01
Completion
2010-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lamivudine Other / unclassified 150 mg Oral
Subject apricitabine Small molecule 800 mg Oral