Irbesartan and Adhesion Molecules in AF

Summary

Experimental data suggest that angiotensin II-antagonists reduce the atrial expression of prothrombotic adhesion molecules and oxidative stress parameters. The present study is designed to investigate the effects on angiotensin II-antagonist irbesartan to reduce the amounts of circulating oxidative stress markers and adhesion molecules in patients with persistent atrial fibrillation.

Timeline

Start

2009-05

Primary completion

2010-05

Completion

2010-05

Drugs

Indications