drugset
drugset / Trial / NCT00617552

Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery

NCT00617552 ↗

Phase 2 Completed 267 enrolled Tranzyme, Inc.
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to determine whether TZP-101 is effective in the management of post operative ileus in subjects undergoing major open abdominal surgery (i.e. partial large bowel resection).

Timeline

Start
2007-07
Primary completion
2008-07
Completion
2008-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Ulimorelin Small molecule 20 ug/kg Intravenous
Subject Ulimorelin Small molecule 40 ug/kg Intravenous
Subject Ulimorelin Small molecule 80 ug/kg Intravenous
Subject Ulimorelin Small molecule 160 ug/kg Intravenous
Subject Ulimorelin Small molecule 320 ug/kg Intravenous
Subject Ulimorelin Small molecule 480 ug/kg Intravenous
Subject Ulimorelin Small molecule 600 ug/kg Intravenous

Indications

ileus