drugset / Trial / NCT00619021
Bronchial Artery Infusion of Gemcitabine in Treating Patients With Recurrent or Progressive Non-Small Cell Lung Cancer
Non-randomizedSingle-groupOpen-labelTreatment
Summary
RATIONALE: Bronchial artery infusion uses a catheter to deliver antitumor substances directly to the lungs. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving gemcitabine in different ways may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of gemcitabine given by bronchial artery infusion and to see how well it works in treating patients with recurrent or progressive non-small cell lung cancer.
Timeline
- Start
- 2003-01
- Primary completion
- 2009-01
- Completion
- 2009-01
Outcome
Outcome not reported
Stopped (Business): “Funding and study drugs unavailable”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gemcitabine | Small molecule | 600 mg/m2 | Other |
| Subject | Gemcitabine | Small molecule | 800 mg/m2 | Other |
| Subject | Gemcitabine | Small molecule | 1000 mg/m2 | Other |
| Subject | Gemcitabine | Small molecule | 1200 mg/m2 | Other |