drugset / Trial / NCT00622479
Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia.
Non-randomizedSingle-groupOpen-labelBasic science
Summary
The purpose of this study is to: 1. To elucidate the mechanism involved in the sorafenib-induced hypophosphatemia and possible early effect of hypophosphatemia on bone mineral density 2. A secondary objective to assess the effect sorafenib treatment on evaluate left ventricular function (LVEF) and Beta-type natriuretic peptide in plasma.
Timeline
- Start
- 2008-05
- Primary completion
- 2010-10
- Completion
- 2010-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sorafenib | Small molecule | 400 mg | — |