drugset / Trial / NCT00627952
A Study to Evaluate the Effects of Manidipine Versus Amlodipine and the Combination of Manidipine Plus Delapril Versus Amlodipine Plus Delapril on Intraglomerular Pressure in Hypertensive Patients
Phase 3
Completed
100 enrolled
University of Erlangen-Nürnberg Medical School
Chiesi Farmaceutici S.p.A. · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Eight-week multi-national, multicenter, randomized, double blind, active control, two arms, parallel groups study with a 4-week single drug treatment (manidipine or amlodipine) phase followed by a 4-week combination treatment (manidipine + delapril or amlodipine + delapril) phase.
Timeline
- Start
- 2007-11
- Primary completion
- 2008-12
- Completion
- 2008-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amlodipine | Other / unclassified | 5 mg | — |
| Comparator | Amlodipine | Other / unclassified | 10 mg | — |
| Comparator | Delapril | Small molecule | 30 mg | — |
| Comparator | MANIDIPINE 6300 | Small molecule | 10 mg | — |
| Comparator | MANIDIPINE 6300 | Small molecule | 20 mg | — |